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Article

Human adipose-derived mesenchymal stromal cells improved wound healing in enterocutaneous fistulizing disease mouse model

2024-11-08

Abstract excerpt

A significant complication of Crohn disease is the formation of perianal fistulas. While local application of human adipose tissue-derived mesenchymal stromal cells (AT-MSC INN Darvadstrocel, Takeda) is an approved therapy for this condition, challenges in studying human clinical tissue and the absence of a robust experimental model have hindered deeper understanding of the preclinical efficacy and mechanisms behi...

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Literature Corpus work
a6c40584-218f-51a9-afcc-03c0af2ac43e
DOI
10.1101/2024.11.07.622127
Open publication

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Human adipose-derived mesenchymal stromal cells improved wound healing in enterocutaneous fistulizing disease mouse modelDOI 10.1101/2024.11.07.622127
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