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Article

Crohn's Disease Disturbs the Immune Properties of Human Adipose-Derived Stem Cells Related to Inflammasome Activation.

Stem cell reports - 10 Oct 2017

Serena Carolina, Keiran Noelia, Madeira Ana, Maymó-Masip Elsa, Ejarque Miriam, Terrón-Puig Margarida, Espin Eloy, Martí Marc, Borruel Natalia, Guarner Francisco, Menacho Margarida, Zorzano Antonio, Millan Monica, Fernández-Veledo Sonia, Vendrell Joan

Abstract excerpt

Crohn's disease (CD) is characterized by the expansion of mesenteric fat, also known as "creeping fat." We explored the plasticity and immune properties of adipose-derived stem cells (ASCs) in the context of CD as potential key players in the development of creeping fat. Mesenteric CD-derived ASCs presented a more proliferative, inflammatory, invasive, and phagocytic phenotype than equivalent cells from healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28966116
DOI: 10.1016/j.stemcr.2017.07.014
PMCID: PMC5639166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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