Article

Standardized pipeline for establishing, expanding, and differentiating airway and alveolar organoids from human BAL fluid

2025-10-15

Abstract excerpt

Lung organoids are versatile experimental models, but their broader use in studying human disease is limited by the scarcity of starting material and the complexity of current methods. To align organoid technology with common clinical practice, we developed airway and alveolar organoids using cells obtained from patients' bronchoalveolar lavage (BAL) fluid. Building on existing techniques, we showed that BAL is a...

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Literature Corpus work: 3cac01d8-1797-52e8-8186-dfcf93d2d678
DOI: 10.1101/2025.10.13.682184

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