Article
Th17 cells contribute to pulmonary fibrosis and inflammation during chronic kidney disease progression after acute ischemia.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Feb 2018
Mehrotra Purvi, Collett Jason A, Gunst Susan J, Basile David P
Abstract excerpt
Acute kidney injury (AKI) is associated with high mortality rates and predisposes development of chronic kidney disease (CKD). Distant organ damage, particularly in the lung, may contribute to mortality in AKI patients. Animal models of AKI demonstrate an increase in pulmonary infiltration of lymphocytes and reveal an acute compromise of lung function, but the chronic effects of AKI on pulmonary inflammation are...
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