Article
Association of 3p21.31 Locus (CXCR6 and LZTFL1) with COVID-19 Outcomes in Brazilian Hospitalyzed Subjects.
Current microbiology - 14 Aug 2023
de Araújo João Locke Ferreira, Bonifácio Victória Frigério, Batista Lorena Medeiros, de Ávila Renata Eliane, Aguiar Renato Santana, Bastos-Rodrigues Luciana, de Souza Renan Pedra
Abstract excerpt
The 3p21.31 locus has been associated with severe COVID-19 prognosis in GWAS studies. Here, we evaluated whether three polymorphisms (LZTFL1 rs10490770, CXCR6 rs2234355 and rs2234358) in the reported locus were associated with the need for mechanical ventilation, hospitalization length and death in 102 COVID-19 hospitalized Brazilian subjects. No genetic association was found with the need for mechanical...
Read the complete abstract on PubMed