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Multi-ancestry Genome-wide Association Study of Varicose Veins Reveals Polygenic Architecture, Genetic Overlap with Arterial and Venous Disease, and Novel Therapeutic Opportunities

2022-02-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Varicose veins represent a common cause of cardiovascular morbidity, with limited available medical therapies. Although varicose veins are heritable and epidemiologic studies have identified several candidate varicose veins risk factors, the molecular and genetic basis remains uncertain. Here, we analyzed the contribution of common genetic variants to varicose veins using data...

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Literature Corpus work
a601959f-581c-5d6c-9dcf-7844919cd761
DOI
10.1101/2022.02.22.22271350
Open publication

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Multi-ancestry Genome-wide Association Study of Varicose Veins Reveals Polygenic Architecture, Genetic Overlap with Arterial and Venous Disease, and Novel Therapeutic OpportunitiesDOI 10.1101/2022.02.22.22271350
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