Article

Varicose veins of lower extremities: insights from the first large-scale genetic study

2018-07-13

Abstract excerpt

Varicose veins of lower extremities (VVs) are a common multifactorial vascular disease. Genetic factors underlying VVs development remain largely unknown. Here we report the first large-scale study of VVs performed on a freely available genetic data of 408,455 European-ancestry individuals. We identified 7 reliably associated loci that explain 10% of the SNP-based heritability, and prioritized the most likely caus...

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Literature Corpus work: 98690aba-2682-5558-89df-758e1650f0ce
DOI: 10.1101/368365

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