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Article

Genome-wide association studies in chronic venous disease: A systematic review.

Journal of vascular surgery. Venous and lymphatic disorders - 1 Mar 2026

Soh Chien Lin, Tan Matthew, Davies Alun H, Onida Sarah

Abstract excerpt

BACKGROUND: Chronic venous disease (CVD) arises from venous hypertension secondary to impaired venous return, causing significant morbidity and diminished quality of life. Genetic factors are likely important in the pathogenesis and susceptibility of a patient to develop CVD. This systematic review summarizes genome-wide association studies (GWASs) that investigate the link between genetic variants and CVD....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41391741
DOI: 10.1016/j.jvsv.2025.102365
PMCID: PMC12830204

Genes

CASZ1
EBF1
GATA2
GJD3
MMP10
PIEZO1
STIM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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