Integrative analysis prioritizes the relevant genes and risk factors for chronic venous disease.

Abstract excerpt

OBJECTIVE: Chronic venous disease (CVD) refers to a range of symptoms resulting from long-term morphological and functional abnormalities of the venous system. However, the mechanism of CVD development remains largely unknown. Here, we aim to provide more information on CVD pathogenesis, prevention strategies, and therapy development through the integrative analysis of large-scale genetic data. METHODS: Genetic...

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• DNA-Binding Proteins
• Genome-Wide Association Study
• Heat-Shock Proteins
• Mendelian Randomization Analysis
• Molecular Chaperones