Article
Pathophysiology and Genetic Associations of Varicose Veins: A Narrative Review.
Angiology - 1 Aug 2025
Chen Tao, Liu Peng, Zhang Chenguang, Jin Song, Kong Yuhu, Feng Yanan, Sun Ziqiang
Abstract excerpt
Varicose veins (VVs) have a high prevalence worldwide and have become a major medical burden. Their pathophysiology involves a complex interplay of inflammation and tissue remodeling, and current treatment is limited by its impact on the pathophysiological mechanisms. In addition, despite clear environmental factors, family history is an important risk factor, suggesting a genetic component to the risk of...
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