Article

Genetic analyses of SERPINA5 in Alzheimer’s disease

2021-08-17

Abstract excerpt

<title>Abstract</title> <p>Alzheimer’s disease (AD) is a progressive neurodegenerative disease that is the most common cause of dementia. Our previous studies have shown that increased expression of the <italic>SERPINA5</italic> gene is associated with hippocampal vulnerability in AD, and that the SERPINA5 protein binds to tau and co-localizes within neurofibrillary tangles. To determine if genetic variants in th...

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Literature Corpus work: a5d47194-136f-5ac3-8c68-33be895ecf85
DOI: 10.21203/rs.3.rs-769744/v1

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