Article

Dysfunctional T Follicular Helper Cells Cause Intestinal and Hepatic Inflammation in NASH

2023-06-09

Abstract excerpt

<h4>ABSTRACT</h4> Nonalcoholic steatohepatitis (NASH), characterized by hepatic inflammation and cellular damage, is the most severe form of nonalcoholic fatty liver disease and the fastest-growing indication for a liver transplant. The intestinal immune system is a central modulator of local and systemic inflammation. In particular, Peyer’s patches (PPs) contain T follicular helper (Tfh) cells that support germi...

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Literature Corpus work: a5c3e6a1-a0a8-5494-89d7-7a30df608c63
DOI: 10.1101/2023.06.07.544061

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