Back to search

Article

Functional modulation of T follicular cells <i>in vivo</i> enhances antigen-specific humoral immunity

2020-11-17

Abstract excerpt

Generation of high-affinity IgG is essential for defense against infections and cancer, is the intended consequence of many vaccines, but can cause autoimmune and inflammatory diseases when inappropriately directed against self (Wang et al., 2018, Ludwig et al., 2017, Chinen et al., 2010). The interplay and balance of T follicular helper cells (T FH ) and T follicular regulatory cells (T FR ) is critical for pro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
03f31679-5fa0-5132-af16-57d28e5dfa90
DOI
10.1101/2020.11.17.387100
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Functional modulation of T follicular cells <i>in vivo</i> enhances antigen-specific humoral immunityDOI 10.1101/2020.11.17.387100
Recombinant IgG1 Fc-μTP-L309C Ameliorates Endogenous Rheumatoid Arthritis in the K/BxN Mouse Model by Decreasing Th1 and Th17 Cells in the Spleen, Lymph Nodes and Joint and Increasing T Regulatory Cells and IL-10 in the JointSemantic proximity
Recombinant IgG1 Fc-μTP-L309C Ameliorates Endogenous Rheumatoid Arthritis in the K/BxN Mouse Model by Decreasing Th1 and Th17 Cells in the Spleen, Lymph Nodes and Joint and Increasing T Regulatory Cells and IL-10 in the JointSemantic proximity
IL-1β Signalling Modulates T Follicular Helper and Regulatory Cells in Human Lymphoid TissuesSemantic proximity
T follicular regulatory cells in mice and men.Semantic proximity
High-affinity, neutralizing antibodies to SARS-CoV-2 can be made in the absence of T follicular helper cellsSemantic proximity
Toll-like receptor 9 signaling acts on multiple elements of the germinal center to enhance antibody responses.Semantic proximity
Targeting the APRIL-BAFF axis in IgA nephropathy: preclinical insights from influenza challenge and single-cell spatial profilingSemantic proximity
Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cellsSemantic proximity
Follicular helper- and peripheral helper-like T cells drive autoimmune disease in human immune system miceSemantic proximity
The expansion in lymphoid organs of IL-4 <sup>+</sup> BATF+ T follicular helper cells is linked to IgG4 class switching <i>in vivo</i>Semantic proximity
Understanding the role of T follicular helper cells in the development and maintenance of chronic allergic airway diseaseSemantic proximity
Antibody Fc: Linking Adaptive and Innate ImmunitySemantic proximity
Select a neighboring publication to make it the new centre.