Article
The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord.
Development (Cambridge, England) - 1 Mar 2016
Petracca Yanina L, Sartoretti Maria Micaela, Di Bella Daniela J, Marin-Burgin Antonia, Carcagno Abel L, Schinder Alejandro F, Lanuza Guillermo M
Abstract excerpt
Considerable progress has been made in understanding the mechanisms that control the production of specialized neuronal types. However, how the timing of differentiation contributes to neuronal diversity in the developing spinal cord is still a pending question. In this study, we show that cerebrospinal fluid-contacting neurons (CSF-cNs), an anatomically discrete cell type of the ependymal area, originate from...
Topics
- Animals
- Cell Differentiation
- Cell Lineage
- Cerebrospinal Fluid
- Electrophysiology
- Eye Proteins
- Female
- Forkhead Transcription Factors
- GATA2 Transcription Factor
- Genotype