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Pan-Cancer Expression Analysis of the Aminoadipate-semialdehyde synthase (AASS) Gene: Insights into its Potential Role in Oncogenic Metabolic Reprogramming

2025-12-01

Abstract excerpt

<title>Abstract</title> <p>Background Metabolic reprogramming is a hallmark of cancer, yet the role of AASS, the rate-limiting enzyme in lysine degradation, remains uncharacterized in a pan-cancer context. This study aimed to define the expression, prognostic significance, and functional network of AASS across human malignancies. Methods A comprehensive bioinformatic analysis was performed using transcriptomic an...

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Literature Corpus work
a5aa6ddc-a248-5a52-8a89-8e21799e30e1
DOI
10.21203/rs.3.rs-8210982/v1
Open publication

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Pan-Cancer Expression Analysis of the Aminoadipate-semialdehyde synthase (AASS) Gene: Insights into its Potential Role in Oncogenic Metabolic ReprogrammingDOI 10.21203/rs.3.rs-8210982/v1
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