Article

Pan-cancer analysis of the metabolic reaction network

2016-04-26

Abstract excerpt

<h4>ABSTRACT</h4> Metabolic reprogramming is considered a hallmark of malignant transformation. However, it is not clear whether the network of metabolic reactions expressed by cancers of different origin differ from each other nor from normal human tissues. In this study, we reconstructed functional and connected genome-scale metabolic models for 917 primary tumors based on the probability of expression for 3,76...

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Literature Corpus work: 03f3181a-a900-514c-99b1-16d815b4e5c9
DOI: 10.1101/050187

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