Article

Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human <i>KRT8/18</i>

2020-01-28

Abstract excerpt

Genome wide association studies for non-syndromic orofacial cleft (OFC) have identified single nucleotide polymorphisms (SNPs) at loci where the presumed risk-relevant gene is expressed in oral periderm. The functional subsets of such SNPs are difficult to predict because the sequence underpinnings of periderm enhancers are unknown. We applied ATAC-seq to models of human palate periderm, including zebrafish peride...

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Literature Corpus work: a59e5bad-f815-5ea4-ab98-2a7f261f8894
DOI: 10.1101/2020.01.27.921320

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