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Article

The Functional Impact of the Noncoding SNP rs3741442 on Orofacial Clefting.

Journal of dental research - 1 Nov 2025

Funato N, Twigg S R F

Abstract excerpt

Orofacial cleft (OFC) is a common congenital anomaly in humans with variable birth prevalence in different ethnic groups. Although genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with nonsyndromic OFC (nsOFC), understanding of the underlying biological mechanisms of causative SNPs and genes in nsOFC remains limited. Here, we report that the noncoding SNP,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40353495
DOI: 10.1177/00220345251334385
PMCID: PMC12508504

Genes

EIF4B
KRT18
SP1
TP63

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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The Functional Impact of the Noncoding SNP rs3741442 on Orofacial Clefting.PMID 40353495Read ↗

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