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SARS-CoV-2 hijacks p38β/MAPK11 to promote virus replication

2021-08-20

Abstract excerpt

SARS-CoV-2, the causative agent of the COVID-19 pandemic, drastically modifies infected cells in an effort to optimize virus replication. Included is the activation of the host p38 mitogen-activated protein kinase (MAPK) pathway, which plays a major role in inflammation and is a central driver of COVID-19 clinical presentations. Inhibition of p38/MAPK activity in SARS-CoV-2-infected cells reduces both cytokine pro...

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Identifiers and source

Literature Corpus work
bd414481-6b56-5a4b-b14e-b0d84ca21f08
DOI
10.1101/2021.08.20.457146
Open publication

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SARS-CoV-2 hijacks p38β/MAPK11 to promote virus replicationDOI 10.1101/2021.08.20.457146
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