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SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis

27 Dec 2022

Abstract excerpt

The coronavirus disease 2019 (COVID-19) pandemic has devastated global health. Identifying key host factors essential for SARS-CoV-2 RNA replication is expected to unravel cellular targets for the development of broad-spectrum antiviral drugs which have been quested for the preparedness of future viral outbreaks. Here, we have identified host proteins that associate with nonstructural protein 12 (nsp12), the...

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PMID: 36575184
DOI: 10.1038/s41392-022-01239-w

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