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Article

Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity

2020-10-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> In the present study, we sought to identify causal relationships between obesity and other complex traits and conditions using a data-driven hypothesis-free approach that uses genetic data to infer causal associations. <h4>Methods</h4> We leveraged available summary-based genetic data from genome-wide association studies on 1,498 phenotypes and applied the latent causal variabl...

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Literature Corpus work
a58bd6a5-4a4f-51ff-a820-7434fd16de1a
DOI
10.1101/2020.10.20.20216598
Open publication

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Phenome-wide screening of GWAS data reveals the complex causal architecture of obesityDOI 10.1101/2020.10.20.20216598
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