Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causal relationships between obesity and the leading causes of death in women and men.

PLoS genetics - 1 Oct 2019

Censin Jenny C, Peters Sanne A E, Bovijn Jonas, Ferreira Teresa, Pulit Sara L, Mägi Reedik, Mahajan Anubha, Holmes Michael V, Lindgren Cecilia M

Abstract excerpt

Obesity traits are causally implicated with risk of cardiometabolic diseases. It remains unclear whether there are similar causal effects of obesity traits on other non-communicable diseases. Also, it is largely unexplored whether there are any sex-specific differences in the causal effects of obesity traits on cardiometabolic diseases and other leading causes of death. We constructed sex-specific genetic risk...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Stroke
Share to Waist-Hip Ratio

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Pulmonary Disease, Chronic Obstructive

Share to Adiposity

Share to Blood Pressure

Share to Cause of Death

Share to Coronary Artery Disease

Share to Mendelian Randomization Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 31647808
DOI: 10.1371/journal.pgen.1008405
PMCID: PMC6812754

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal relationships between obesity and the leading causes of death in women and men.PMID 31647808Read ↗

Causal relevance of obesity on the leading causes of death in women and men: A Mendelian randomization studySemantic proximity Read ↗

Novel insights into the consequences of obesity: a phenotype-wide Mendelian randomization study.Semantic proximity Read ↗

Risk factors mediating the effect of body mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysisSemantic proximity Read ↗

Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk FactorsSemantic proximity Read ↗

Genetically versus environmentally influenced obesity and risk of mortality and non-communicable diseases: A cohort study from the UK BiobankSemantic proximity Read ↗

Risk factors mediating the effect of body-mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysisSemantic proximity Read ↗

Causal role of high body mass index in multiple chronic diseases: a systematic review and meta-analysis of Mendelian randomization studies.Semantic proximity Read ↗

Joint and interactive associations of body mass index and genetic factors with cardiovascular disease: a prospective study in UK Biobank.Semantic proximity Read ↗

Analyses of potential causal contributors to increased waist/hip ratio-associated cardiometabolic disease: A combined and sex-stratified Mendelian randomization study.Semantic proximity Read ↗

Comparative Analysis of Surrogate Adiposity Markers and Their Relationship With MortalitySemantic proximity Read ↗

Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.Semantic proximity Read ↗

Body mass index, waist circumference, and mortality in subjects older than 80 years: a Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.