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Article

An integrative framework to prioritize genes in more than 500 loci associated with body mass index.

American journal of human genetics - 6 Jun 2024

Hemerich Daiane, Svenstrup Victor, Obrero Virginia Diez, Preuss Michael, Moscati Arden, Hirschhorn Joel N, Loos Ruth J F

Abstract excerpt

Obesity is a major risk factor for a myriad of diseases, affecting >600 million people worldwide. Genome-wide association studies (GWASs) have identified hundreds of genetic variants that influence body mass index (BMI), a commonly used metric to assess obesity risk. Most variants are non-coding and likely act through regulating genes nearby. Here, we apply multiple computational methods to prioritize the likely...

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Identifiers

PMID: 38754426
DOI: 10.1016/j.ajhg.2024.04.016
PMCID: PMC11179420

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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