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Thrombocytopenia in murine schistosomiasis is associated with platelet uptake by liver macrophages that have a distinct activation phenotype

2024-11-03

Abstract excerpt

Alongside their well-established role in hemostasis, platelets are key modulators of immune cell function. This is particularly the case for macrophages, as platelets can either promote or dampen macrophage activation in a context-specific manner. Whilst the role of platelets in modulating classical (M1) macrophage activation following bacterial challenge is relatively well understood, whether platelets control ot...

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Literature Corpus work
a570e7de-c22f-563f-9075-388dafe8ce2f
DOI
10.1101/2024.10.29.620826
Open publication

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Thrombocytopenia in murine schistosomiasis is associated with platelet uptake by liver macrophages that have a distinct activation phenotypeDOI 10.1101/2024.10.29.620826
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