Article
Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype.
Frontiers in immunology - 1 Jan 2018
Cortes-Selva Diana, Elvington Andrew F, Ready Andrew, Rajwa Bartek, Pearce Edward J, Randolph Gwendalyn J, Fairfax Keke C
Abstract excerpt
Hepatic macrophages play an essential role in the granulomatous response to infection with the parasitic helminth Schistosoma mansoni, but the transcriptional changes that underlie this effect are poorly understood. To explore this, we sorted the two previously recognized hepatic macrophage populations (perivascular and Kupffer cells) from naïve and S. mansoni-infected male mice and performed microarray analysis...
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