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Article

Dynamic changes in macrophage activation and proliferation during the development and resolution of intestinal inflammation.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2014

Little Matthew C, Hurst Rebecca J M, Else Kathryn J

Abstract excerpt

Macrophages (Mφs) accumulate at sites of inflammation, and, because they can assume several functionally distinct states of activation, they can either drive or restrain inflammatory responses. Once believed to depend on the recruitment of blood monocytes, it is now clear that the accumulation of Mφs in some tissues can result from the proliferation of resident Mφs in situ. However, little is known about the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25261482
DOI: 10.4049/jimmunol.1400502
PMCID: PMC4201944

Genes

CCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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