Article

Schistosome tegumental ecto-apyrase (SmATPDase1) degrades exogenous pro-inflammatory and pro-thrombotic nucleotides.

2014-01-14

Abstract excerpt

Schistosomes are parasitic worms that can survive in the hostile environment of the human bloodstream where they appear refractory to both immune elimination and thrombus formation. We hypothesize that parasite migration in the bloodstream can stress the vascular endothelium causing this tissue to release chemicals alerting responsive host cells to the stress. Such chemicals are called damage associated molecular...

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Literature Corpus work: c7e6a2fb-5e73-5dfe-95b0-d7bb5be9adfb
DOI: 10.7287/peerj.preprints.201v1

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