Article

A targetable developmental program co-regulates angiogenesis and immune evasion

2024-12-21

Abstract excerpt

<h4>ABSTRACT</h4> Ultraviolet (UV)-induced DNA mutations produce genetic drivers of cutaneous melanoma initiation and numerous neoantigens that can trigger anti-tumor immune responses in the host. Consequently, melanoma cells must rapidly evolve to evade immune detection by simultaneously modulating cell-autonomous epigenetic mechanisms and tumor-microenvironment interactions. Angiogenesis has been implicated in...

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Literature Corpus work: a4a32996-01e0-545f-991a-7d465dc3bd9f
DOI: 10.1101/2024.12.21.628442

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