Article

Abnormal TNS3 gene methylation in patients with congenital scoliosis

2022-04-11

Abstract excerpt

<h4>Background: </h4> Congenital scoliosis (CS) is a congenital deformity of the spine resulting from an abnormal and asymmetrical development of vertebral bodies during pregnancy. However, the etiology and mechanism of CS are still unclear. Epigenetics is the study of heritable variations in gene expression outside of changes in nucleotide sequence. Among these, DNA methylation is the longest known, most characte...

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Literature Corpus work: a4899e79-989d-52c5-ac7c-94dc051e5d44
DOI: 10.21203/rs.3.rs-1527947/v1

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