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Article

High methylation of lysine acetyltransferase 6B is associated with the Cobb angle in patients with congenital scoliosis

24 May 2020

Abstract excerpt

BACKGROUND: The etiology of congenital scoliosis (CS) is complex and uncertain. Abnormal DNA methylation affects the growth and development of spinal development. In this study, we investigated the role of DNA methylation in CS. METHODS: The target region DNA methylation level in the peripheral blood of patients with CS was analyzed. Through in-depth analysis, genes closely related to the growth and development...

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PMID: 32448279
DOI: 10.1186/s12967-020-02367-z

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