Article

Characterisation and prognostic impact of ZRSR2 mutations in myeloid neoplasms

2024-07-15

Abstract excerpt

<title>Abstract</title> <p>The ZRSR2 gene is a member of the spliceosome gene family which are frequently mutated in myeloid neoplasms. <italic>ZRSR2</italic> mutations (<italic>ZRSR2m</italic>) occur in less than 5% of MDS, CMML, and AML. Our study included 164 <italic>ZRSR2m</italic> patients (98.8% males) and 98 <italic>ZRSR2wt</italic> MDS control cohort. In the <italic>ZRSR2m</italic> group, there were 53 MD...

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Literature Corpus work: a488f4e7-c2a7-5e0a-bb41-699e0015e4f2
DOI: 10.21203/rs.3.rs-4590446/v1

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