Article

Entorhinal cortex epigenome-wide association study highlights four novel loci showing differential methylation in Alzheimer’s disease

2021-07-03

Abstract excerpt

<h4>Background</h4> Studies on DNA methylation (DNAm) in Alzheimer’s disease (AD) have recently highlighted several genomic loci showing association with disease onset and progression. <h4>Methods</h4> Here, we conducted an epigenome-wide association study (EWAS) using DNAm profiles in entorhinal cortex (EC) from 149 AD patients and control brains and combined these with two previously published EC datasets by m...

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Literature Corpus work: a4719e79-f842-548e-8819-ef41bbfaf3d3
DOI: 10.1101/2021.07.02.450878

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