Article

TNFSF14/LIGHT, a Non-Canonical NF-kB Stimulus, Induces the HIF Pathway

2018-07-02

Abstract excerpt

Non-canonical NF-kB signalling plays important roles in development and function of the immune system but also is deregulated in a number of inflammatory diseases. Although, NF-kB and HIF crosstalk has been documented, this has only been described following canonical NF-kB stimulation, involving RelA/p50 and the HIF-1 dimer. Here we report that the non-canonical inducer TNFSF14/LIGHT leads to HIF induction and act...

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Literature Corpus work: a470f9b6-f6d1-5534-9cc9-0ec766148265
DOI: 10.20944/preprints201807.0007.v1

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