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At the Crossroads of TNF α Signaling and Cancer

11 Sept 2023

Abstract excerpt

Tumor necrosis factor-alpha (TNFα) is a pleiotropic pro-inflammatory cytokine of the TNF superfamily. It regulates key cellular processes such as death, and proliferation besides its well-known role in immune response through activation of various intracellular signaling pathways (such as MAPK, Akt, NF-κB, etc.) via complex formation by ligand-activated TNFα receptors. TNFα tightly regulates the activity of key...

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PMID: 37691196
DOI: 10.2174/1874467217666230908111754

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