Article

HIF-1beta Positively Regulates NF-kappaB Activity via Direct Control of TRAF6

2020-03-10

Abstract excerpt

NF-B signalling is crucial for cellular responses to inflammation but has also been associated with the hypoxia response. NF-B and HIF transcription factors possess an intense molecular crosstalk. Although it is known that HIF-1beta modulates NF-kappaB transcriptional response, very little is understood regarding how HIF-1beta contributes to NF-kappaB signalling. Here, we demonstrate that HIF-1beta is required f...

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Literature Corpus work: 7127b588-2c31-5080-86f4-590162130d17
DOI: 10.20944/preprints202003.0168.v1

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