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Article

The role of hypoxia in inflammatory disease (Review)

17 Jan 2015

Abstract excerpt

Mammals have developed evolutionarily conserved programs of transcriptional response to hypoxia and inflammation. These stimuli commonly occur together in vivo and there is significant crosstalk between the transcription factors that are classically understood to respond to either hypoxia or inflammation. This crosstalk can be used to modulate the overall response to environmental stress. Several common disease...

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PMID: 25625467
DOI: 10.3892/ijmm.2015.2079

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