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Article

TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.

The Journal of biological chemistry - 19 Sept 2003

Saitoh Tatsuya, Nakayama Masafumi, Nakano Hiroyasu, Yagita Hideo, Yamamoto Naoki, Yamaoka Shoji

Abstract excerpt

Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK) is a member of the TNF superfamily that has been shown to induce angiogenesis, apoptosis in tumor cells, and NF-kappaB activation through binding to its receptor, fibroblast growth factor-inducible 14. We have identified TWEAK as an inducer of constitutive NF-kappaB activation by expression cloning, and we report here sequential regulation by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12840022
DOI: 10.1074/jbc.M304266200

Genes

TNF
TRAF2
TRAF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TWEAK induces NF-kappaB2 p100 processing and long lasting NF-kappaB activation.PMID 12840022Read ↗

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