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LRP3, an apolipoprotein receptor that links reelin signalling and APP expression, is affected in Alzheimer's disease

2021-02-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>. Members of the low-density lipoprotein (LDL) receptor family are involved in endocytosis and in transducing signals, but also in APP (amyloid precursor protein) processing and β-amyloid secretion. ApoER2/LRP8 is a member of this family with key roles in synaptic plasticity in the adult brain. ApoER2 is cleaved after the binding of its ligand, the reelin protein,...

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Literature Corpus work
a4370be6-b0d6-5e88-b2aa-fa44d0f62cf0
DOI
10.21203/rs.3.rs-220026/v1
Open publication

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LRP3, an apolipoprotein receptor that links reelin signalling and APP expression, is affected in Alzheimer's diseaseDOI 10.21203/rs.3.rs-220026/v1
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