Article

Naloxone Reversed Orofacial Analgesia Induced by Treadmill Exercise in a Rat Model of Parkinson's Disease: Exploring Opioid Receptors Involvement

2026-04-20

Abstract excerpt

<title>Abstract</title> <p>Exercise-induced analgesia has been consistently associated with the activation of endogenous opioid pathways; however, the specific contribution of opioid receptor signaling to the reduction of orofacial pain in Parkinsonian conditions remains incompletely understood. Therefore, this study investigated whether pharmacological blockade of opioid receptors reverses the antinociceptive ef...

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Literature Corpus work: a4349c7a-0ca7-555e-9d0b-a7c2579ed447
DOI: 10.21203/rs.3.rs-9452205/v1

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