Article

Forced exercise activates the NrF2 pathway in the striatum and ameliorates motor and behavioral manifestations of Parkinson's disease in rotenone-treated rats

2020-04-07

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Parkinson's disease (PD) is a common neurodegenerative disorder characterized by progressive loss of nigrostriatal dopaminergic neurons leading to dopamine depletion and problems of movement, emotions and cognition. While the pathogenesis of PD is not clear, damage of dopaminergic neurons by oxygen-derived free radicals is considered an important contributing me...

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Literature Corpus work: 93fb64c9-47b0-5485-9260-e9d846e9c739
DOI: 10.21203/rs.3.rs-20921/v1

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