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Article

Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice.

Pharmacological research - 1 Sept 2016

Yang Pao-Pao, Yeh Geng-Chang, Yeh Teng-Kuang, Xi Jinghua, Loh Horace H, Law Ping-Yee, Tao Pao-Luh

Abstract excerpt

Oxycodone has been used clinically for over 90 years. While it is known that it exhibits low affinity for the multiple opioid receptors, whether its pharmacological activities are due to oxycodone activation of the opioid receptor type or due to its active metabolite (oxymorphone) that exhibits high affinity for the mu-opioid receptors remains unresolved. Ross and Smith (1997) reported the antinociceptive effects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Opioid, delta

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Source

Identifiers

PMID: 27496654
DOI: 10.1016/j.phrs.2016.05.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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