Article
Effect of peripheral axotomy on dorsal root ganglion neuron phenotype and autonomy behaviour in neuropeptide Y-deficient mice.
Regulatory peptides - 25 Sept 1998
Shi T J, Zhang X, Berge O G, Erickson J C, Palmiter R D, Hökfelt T
Abstract excerpt
The lumbar 5 (L5) dorsal root ganglia (DRGs) were studied in neuropeptide tyrosine (NPY)-deficient (-/-) and wild type (+/+) mice after unilateral sciatic nerve transection using in situ hybridization and immunohistochemistry. NPY, galanin and two NPY receptors (Y-Rs) were analyzed as well as sel...
Topics
- Animals
- Axotomy
- Base Sequence
- Behavior, Animal
- Female
- Galanin
- Ganglia, Spinal
- In Situ Hybridization
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Neurons
- Neuropeptide Y
- Oligonucleotide Probes
- Pain Threshold
- Phenotype
- RNA, Messenger
- Receptors, Neuropeptide Y