Article
HIPPOCAMPAL DNA METHYLATION, DNAm AGE AND SPATIAL MEMORY PERFORMANCE IN YOUNG AND OLD RATS
2021-05-09
Abstract excerpt
<h4>ABSTRACT</h4> In humans and rats, aging is associated with a progressive deterioration of spatial learning and memory. These functional alterations are correlated with morphological and molecular changes in the brain, particularly in the hippocampus. Here, we assessed the age-related changes in the DNA methylation (DNAm) landscape in the rat hippocampus and assessed the correlation of spatial memory performan...
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Identifiers and source
- Literature Corpus work
- a41ee5f9-de19-596e-9041-82aa1ecd1fd0
- DOI
- 10.1101/2021.05.07.443204
