Article
Epigenetic rejuvenation of the hippocampus by environmental enrichment
2019-09-23
Abstract excerpt
The decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Lifestyle interventions can improve brain function during aging, but their influence on age-related epigenetic changes is unknown. Using genome-wide DNA methylation sequencing, we here show that environmental enrichment counteracted age-related DNA methylation changes in the hippocampal dentate gyrus of mic...
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Identifiers and source
- Literature Corpus work
- 72f7ed36-c31e-5d51-9886-ab1698194378
- DOI
- 10.1101/776310
