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Article

Stability of Genomic Imprinting and X-Chromosome Inactivation in the Aging Brain

2023-09-30

Abstract excerpt

Epigenetic drift is a hallmark of aging that contributes to the irreversible decline in organismal fitness ultimately leading to aging-related diseases. Epigenetic modifications regulate the cellular memory of the epigenetic processes of genomic imprinting and X-chromosome inactivation to ensure monoallelic expression of imprinted and X-linked genes. Whether epigenetic drift affects maintenance of genomic imprinti...

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Literature Corpus work
37dfba15-1b50-590d-9bd2-48fa9ebe1a7d
DOI
10.1101/2023.09.29.560184
Open publication

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Stability of Genomic Imprinting and X-Chromosome Inactivation in the Aging BrainDOI 10.1101/2023.09.29.560184
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