Article

Behavioral and transcriptomic analyses of mecp2 function in zebrafish

2023-09-15

Abstract excerpt

Rett Syndrome (RTT), a human neurodevelopmental disorder characterized by severe cognitive and motor impairments, is caused by dysfunction of the conserved transcriptional regulator Methyl-CpG-binding protein 2 (MECP2). Genetic analyses in mouse Mecp2 mutants, which exhibit key features of human RTT, have been essential for deciphering the mechanisms of MeCP2 function; nonetheless, our understanding of these compl...

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Literature Corpus work: a3a4ae4d-e3c5-5594-a3eb-8179827d28bd
DOI: 10.1101/2023.09.13.557635

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