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Article

A Forward Genetic Screen in Zebrafish Identifies the G-Protein-Coupled Receptor CaSR as a Modulator of Sensorimotor Decision Making.

Current biology : CB - 7 May 2018

Jain Roshan A, Wolman Marc A, Marsden Kurt C, Nelson Jessica C, Shoenhard Hannah, Echeverry Fabio A, Szi Christina, Bell Hannah, Skinner Julianne, Cobbs Emilia N, Sawada Keisuke, Zamora Amy D, Pereda Alberto E, Granato Michael

Abstract excerpt

Animals continuously integrate sensory information and select contextually appropriate responses. Here, we show that zebrafish larvae select a behavioral response to acoustic stimuli from a pre-existing choice repertoire in a context-dependent manner. We demonstrate that this sensorimotor choice is modulated by stimulus quality and history, as well as by neuromodulatory systems-all hallmarks of more complex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29681477
DOI: 10.1016/j.cub.2018.03.025
PMCID: PMC5940496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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