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Article

The role of MeCP2 in brain development and neurodevelopmental disorders.

Current psychiatry reports - 1 Apr 2010

Gonzales Michael L, LaSalle Janine M

Abstract excerpt

Methyl CpG binding protein-2 (MeCP2) is an essential epigenetic regulator in human brain development. Rett syndrome, the primary disorder caused by mutations in the X-linked MECP2 gene, is characterized by a period of cognitive decline and development of hand stereotypies and seizures following an apparently normal early infancy. In addition, MECP2 mutations and duplications are observed in a spectrum of...

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Identifiers

PMID: 20425298
DOI: 10.1007/s11920-010-0097-7
PMCID: PMC2847695

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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