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Article

A comparison of Cox and logistic regression for use in genome-wide association studies of cohort and case-cohort design.

European journal of human genetics : EJHG - 1 Jun 2017

Staley James R, Jones Edmund, Kaptoge Stephen, Butterworth Adam S, Sweeting Michael J, Wood Angela M, Howson Joanna M M

Abstract excerpt

Logistic regression is often used instead of Cox regression to analyse genome-wide association studies (GWAS) of single-nucleotide polymorphisms (SNPs) and disease outcomes with cohort and case-cohort designs, as it is less computationally expensive. Although Cox and logistic regression models have been compared previously in cohort studies, this work does not completely cover the GWAS setting nor extend to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28594416
DOI: 10.1038/ejhg.2017.78
PMCID: PMC5520083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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