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Article

Ionizing radiation-induced risks to the central nervous system and countermeasures in cellular and rodent models

18 Sept 2020

Abstract excerpt

PURPOSE: Harmful effects of ionizing radiation on the Central Nervous System (CNS) are a concerning outcome in the field of cancer radiotherapy and form a major risk for deep space exploration. Both acute and chronic CNS irradiation induce a complex network of molecular and cellular alterations including DNA damage, oxidative stress, cell death and systemic inflammation, leading to changes in neuronal structure...

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Identifiers

PMID: 32946305
DOI: 10.1080/09553002.2020.1820598

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